• Advertise
  • Contact Us
  • Write For Us
  • Our Team
Extraction Magazine
No Result
View All Result
  • Botanical Extraction
    • Cannabinoids
    • Psychedelics
    • Nutraceutical
    • Product Refinement
  • Industry News
    • Business
    • Sustainability
    • Safety & Compliance
    • Partners
  • Extraction Technology
    • Equipment
    • Methods
    • Solvents
    • DIY Extraction
    • Analytical Techniques
  • Medical Research
  • Glossary
  • Business Directory
  • Botanical Extraction
    • Cannabinoids
    • Psychedelics
    • Nutraceutical
    • Product Refinement
  • Industry News
    • Business
    • Sustainability
    • Safety & Compliance
    • Partners
  • Extraction Technology
    • Equipment
    • Methods
    • Solvents
    • DIY Extraction
    • Analytical Techniques
  • Medical Research
  • Glossary
  • Business Directory
No Result
View All Result
Extraction Magazine
No Result
View All Result
Home Botanical Extraction

Mechanochemical-Assisted Extraction

Derek Johnson by Derek Johnson
April 25, 2021
in Botanical Extraction
Mechanochemical-Assisted Extraction

Efficiency and safety are two issues of central importance when it comes to extracting bio-compounds for food and medicinal purposes. Additionally, extraction methods that are friendly to the environment are just as important as those that are safe and effective which is why mechanochemical-assisted extraction (MCAE) is a desirable way to extract bio-compounds for food and medicine. [1]

MCAE is a relatively new form of extraction. It was first employed in 2003 when Korolev et al [2] used it to extract triterpenic acids. Because the technique uses very little or no organic solvent, it has garnered much attention since its first reported use.

READ ALSO

Collaborative Approaches in Botanical Extraction: Bridging Science and Industry

Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu

MCAE essentially consists of three steps: source material preparation, mechanochemical treatment of the prepared source material, and extraction. [1] During the preparation stage, the raw material is completely dried and then pulverized into fine particles optimally measuring between 0.5-2 mm. [1] According to Zhu et al [3], finer particle sizes are desirable when extracting flavonoids and terpene trilactones from the leaves of the ginkgo plant.

Afterwards, the material is placed in a ball mill and mixed with one of many different reagents. These include sodium carbonate (Na2CO3), sodium bicarbonate (NaHCO3), sodium hydroxide (NaOH), silicon dioxide, (SiO2), or hydroxypropyl-β-cyclodextrin (HP-β-CD), to name a few. [1,4] The choice of reagent depends heavily on the source material to be used. [1] For example, Xie et al [4] demonstrated that NaHCO3 was not as effective as Na2CO3 in pulling flavonoids from bamboo leaves.

The purpose of this second step is to change the chemical nature of the compounds found in the source material to make them more water soluble. [2] Doing so allows the use of water for extraction instead of or alongside of a small amount of chemical solvent, which makes the process of extraction cheaper and safer. After the solution (which is now in salt form due to the reagent) is dissolved in water, it must be returned to its original form. This is accomplished through acidification. [1]

Because it is a relatively new and alternative technique, MCAE needs more study. However, what is known is that its use of water as a solvent and relatively short extraction time make it a very attractive method of extraction. Also, MCAE does not require high temperatures, which are known to degrade or even destroy source materials and their desirable compounds. [1]

 

Image Source: Karolina Grabowska, Pexels

References:

  1. Wu K, et al. Mechanochemical assisted extraction: A novel, efficient, eco-friendly technology. Trends in Food Science and Technology. 2017;66:166-175. [Impact Factor: 11.077; Times Cited: 8 (Semantic Scholar)]
  2. Korolev KG, et al. Mechanochemical preparation of water-soluble forms of triterpene acids. Chemistry of Natural Compounds. 2003;39(4):366–372. [Impact Factor: 653; Times Cited: 30 (Semantic Scholar)]
  3. Zhu X-Y, et al. Response surface optimization of mechanochemical-assisted extraction of flavonoids and terpene trilactones from Ginkgo leaves. Industrial Crops and Products. 2011;34(1):1041–1052. [Impact Factor: 4.244; Times Cited: 25 (Semantic Scholar)]
  4. Xie J, et al. Mechanochemical-assisted extraction of flavonoids from bamboo (Phyllostachys edulis) leaves. Industrial Crops and Products. 2013;43:276–282. [Impact Factor: 4.244; Times Cited: 33 (Semantic Scholar)]

 

Related Posts

Wide angle view at two workers wearing protective suits while inspecting production at modern chemical plant, copy space
Botanical Extraction

Collaborative Approaches in Botanical Extraction: Bridging Science and Industry

January 7, 2025
Areca Catechu
Botanical Extraction

Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu

January 1, 2025
The Art of Extraction: Unlocking Nature’s Fragile Secrets
Botanical Extraction

The Art of Extraction: Unlocking Nature’s Fragile Secrets

December 27, 2024
Kava leaves growing naturally
Botanical Extraction

The Chemical Secrets Behind Kava’s Effects

December 27, 2024
The Use of Psychedelics in Trauma Healing
Medical Research

The Use of Psychedelics in Trauma Healing

December 10, 2024
The Art of Extracting Thermolabile Compounds: Dr. Derek Osei Berchie Interview
Botanical Extraction

The Art of Extracting Thermolabile Compounds: Dr. Derek Osei Berchie Interview

December 2, 2024
Next Post
Quantifying Cannabidiol in Natural Cosmetics

Quantifying Cannabidiol in Natural Cosmetics

LATEST ARTICLES

Green Extraction Techniques

Green Extraction Techniques and Smart Solvents for Bioactive Recovery

January 10, 2025
Wide angle view at two workers wearing protective suits while inspecting production at modern chemical plant, copy space

Collaborative Approaches in Botanical Extraction: Bridging Science and Industry

January 7, 2025
Areca Catechu

Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu

January 1, 2025
The Art of Extraction: Unlocking Nature’s Fragile Secrets

The Art of Extraction: Unlocking Nature’s Fragile Secrets

December 27, 2024

Subscribe Now

Subscribe to our newsletter now to receive quick updates from us



    Background
    About

    Extraction Magazine is the trusted provider of botanical extraction news, ever-changing politics, cool gadgets and technologies, and methods for producing safe, ethical, and compliant formulations.

    Advertisers
    Navigation
    • Botanical Extraction
    • Industry News
    • Extraction Technology
    • Medical Research
    • Glossary
    • Business Directory
    Recent Posts
    • Green Extraction Techniques and Smart Solvents for Bioactive Recovery
    • Collaborative Approaches in Botanical Extraction: Bridging Science and Industry
    • Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu
    • The Art of Extraction: Unlocking Nature’s Fragile Secrets
    Subscribe to our Newsletter
    loader

    Sitemap

    © 2025 Extraction Magazine is the trusted provider of botanical extraction news and the leading media in the ever-changing extraction industry.

    No Result
    View All Result
    • Industry News
    • Botanical Extraction
    • Medical Research
    • Medical Research
    • Glossary
    • Our Team
    • Write For Us

    © 2023 Extraction Magazine is the trusted provider of botanical extraction news and the leading media in the ever-changing extraction industry.