• Advertise
  • Contact Us
  • Write For Us
  • Our Team
Extraction Magazine
No Result
View All Result
  • Botanical Extraction
    • Cannabinoids
    • Psychedelics
    • Nutraceutical
    • Product Refinement
  • Industry News
    • Business
    • Sustainability
    • Safety & Compliance
    • Partners
  • Extraction Technology
    • Equipment
    • Methods
    • Solvents
    • DIY Extraction
    • Analytical Techniques
  • Medical Research
  • Glossary
  • Business Directory
  • Botanical Extraction
    • Cannabinoids
    • Psychedelics
    • Nutraceutical
    • Product Refinement
  • Industry News
    • Business
    • Sustainability
    • Safety & Compliance
    • Partners
  • Extraction Technology
    • Equipment
    • Methods
    • Solvents
    • DIY Extraction
    • Analytical Techniques
  • Medical Research
  • Glossary
  • Business Directory
No Result
View All Result
Extraction Magazine
No Result
View All Result
Home Industry News Safety & Compliance

Does Cannabidiol Help Abstinent Cigarette-Dependent Smokers?

Petar Petrov by Petar Petrov
December 13, 2019
in Safety & Compliance
Does Cannabidiol Help Abstinent Cigarette-Dependent Smokers?

When you look at the negative cognitive symptoms of nicotine abstinence in cigarette-dependent smokers versus the positive effects of cannabidiol (CBD), you might wonder how the latter could help with the former. This is precisely what an insightful study investigated.

READ ALSO

Quality Control of Plant-Derived Products in Industrial Setting

“Novel Food” Regulations For Botanical Products In Europe

Cognitive Symptoms of Nicotine Abstinence in Cigarette-Dependent Smokers

The study examined a few major indicators of the participants’ working memory and impulsivity, which are the two main cognitive processes that nicotine withdrawal takes a toll on, to determine whether CBD actually alleviates the symptoms. [1]

These indicators of impulsivity were delay discounting, which refers to “the degree to which one prefers smaller, immediate rewards over larger, more delayed rewards,” and response inhibition, which is “the ability to stop a pre-potent response (e.g. craving for cigarettes).”

Specific tasks (go/no-go, prose recall, and N-back) were used to measure arithmetic and recognition memory ability, which are the memory aspects that suffer the most when a cigarette-dependent smoker is abstinent. [1]

Why Would CBD Help?

Clearly, the researchers didn’t just randomly stumble upon the idea of using CBD as a potential source of relief for the aforementioned symptoms. On the contrary, previous pertinent studies had shown quite promising results.

From the studies [2,3] the researchers examined, CBD showed promise with alleviating heroin cravings. Furthermore, past studies found that “a single week of ad-hoc CBD via inhaler, compared to placebo, reduced cigarette smoking by almost 40%, however craving was unaffected” [4], while “800 mg oral CBD, in comparison to placebo, reversed attentional bias away cigarette cues, and reduced explicit liking of cigarette stimuli” [5]. And CBD’s ability to “protect against the detrimental cognitive effects of THC” put a stamp on the researchers’ hypothesis. [1]

The Methods

The study involved 30 participants (1:1 men to women) at the average age of 28 who smoked 13.5 cigarettes per day for the past 9.6 years on average. Such a habit is considered moderate-to-high cigarette dependence, which is why nicotine withdrawal was considered acute and posed uncharted territory.

The study implemented a double-blind placebo-controlled crossover design “to compare the effects of 800 mg oral CBD with matched placebo after overnight abstinence.”

The Results

The results were a let-down, especially when you consider CBD’s hypothesized promise. In terms of impulsivity, delay discounting wasn’t improved by CBD; rather, it was 4.6 times likelier for CBD and placebo to have the same effect on nicotine withdrawal. The results of the go/no-go task were even worse — CBD actually increased errors.

As far as memory abilities, CBD didn’t have a positive effect on prose recall or the N-back task, with the null being 3.6 and 5.5 times likelier than the central hypothesis, respectively.

Even though this is not what the researchers and cigarette-dependent people were probably hoping for, it doesn’t definitively say that CBD can’t smooth the edginess of abstinent smokers to a certain extent over time. After all, the study used a single, large dose of CBD for acute rather than sustained abstinence. [1]

Reference:

  1. Hindocha et al. “The Effects of Cannabidiol on Impulsivity and Memory During Abstinence in Cigarette Dependent Smokers.” Scientific Reports, vol.8, no.1, 2018, p.7568. Journal Impact Factor = 4.122; Times Cited = 7
  2. Ren, Y., Whittard, J., Higuera-Matas, A., Morris, C. V. & Hurd, Y. L. “Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances.” The Journal of Neuroscience, vol. 29, no.47, 2009, pp.14764–14769. Journal Impact Factor = 6.074; Times Cited = 92
  3. Hurd, Y. L. et al. “Early Phase in the Development of Cannabidiol as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage.” Neurotherapeutics, vol. 12, no.4, 2015, pp. 807–815, https://doi.org/10.1007/s13311-015-0373-7. Journal Impact Factor = 5.719; Times Cited = 41
  4. Morgan, C. J., Das, R. K., Joye, A., Curran, H. V. & Kamboj, S. K. “Cannabidiol Reduces Cigarette Consumption in Tobacco Smokers: Preliminary Findings.” Addict Behav, vol. 38, no. 9, 2013, pp. 2433–2436. Journal Impact Factor = 2.963; Times Cited = 60
  5. Hindocha, C. et al. “Cannabidiol Reverses Attentional Bias to Cigarette Cues in a Human Experimental Model of Tobacco Withdrawal.” Addiction, vol.113, no.9, 2018, https://doi.org/10.1111/add.14243. Journal Impact Factor = 6.851; Times Cited = 14

Image Credits: HealthAhead

Related Posts

QC in the Cannabis industry 
Industry News

Quality Control of Plant-Derived Products in Industrial Setting

June 20, 2024
What are Novel Foods?
Industry News

“Novel Food” Regulations For Botanical Products In Europe

June 17, 2024
The Role Of The FDA In Drug Approval
Safety & Compliance

The Role Of The FDA In Drug Approval

May 10, 2024
Psychedelics and Mental Health in Australia: Realistically
Industry News

Psychedelics and Mental Health in Australia: Realistically

July 5, 2023
The Approaching Deadline For Canada’s Extraction And Edible Industry
Industry News

The Approaching Deadline For Canada’s Extraction And Edible Industry

May 15, 2023
How to Read CBD Product Labels
Business

How to Read CBD Product Labels

April 18, 2023
Next Post
Puurfx Launches Premium CBD-Curated Subscription Box Service

Puurfx Launches Premium CBD-Curated Subscription Box Service

LATEST ARTICLES

Green Extraction Techniques

Green Extraction Techniques and Smart Solvents for Bioactive Recovery

January 10, 2025
Wide angle view at two workers wearing protective suits while inspecting production at modern chemical plant, copy space

Collaborative Approaches in Botanical Extraction: Bridging Science and Industry

January 7, 2025
Areca Catechu

Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu

January 1, 2025
The Art of Extraction: Unlocking Nature’s Fragile Secrets

The Art of Extraction: Unlocking Nature’s Fragile Secrets

December 27, 2024

Subscribe Now

Subscribe to our newsletter now to receive quick updates from us



    Background
    About

    Extraction Magazine is the trusted provider of botanical extraction news, ever-changing politics, cool gadgets and technologies, and methods for producing safe, ethical, and compliant formulations.

    Advertisers
    Navigation
    • Botanical Extraction
    • Industry News
    • Extraction Technology
    • Medical Research
    • Glossary
    • Business Directory
    Recent Posts
    • Green Extraction Techniques and Smart Solvents for Bioactive Recovery
    • Collaborative Approaches in Botanical Extraction: Bridging Science and Industry
    • Inside the Betel Nut High: Exploring the Mind-Bending Effects of Areca Catechu
    • The Art of Extraction: Unlocking Nature’s Fragile Secrets
    Subscribe to our Newsletter
    loader

    Sitemap

    © 2025 Extraction Magazine is the trusted provider of botanical extraction news and the leading media in the ever-changing extraction industry.

    No Result
    View All Result
    • Industry News
    • Botanical Extraction
    • Medical Research
    • Medical Research
    • Glossary
    • Our Team
    • Write For Us

    © 2023 Extraction Magazine is the trusted provider of botanical extraction news and the leading media in the ever-changing extraction industry.